This is a protocol of a systematic review about communication interventions  to promote the vaccination in low-and middle-income countries. The protocol was developed based on the Preferred Reporting Items for Systematic Reviews and Meta-Analysis Protocols (PRISMA-P) and registered on PROSPERO (CRD42022355541).

Understanding that one of the main obstacles in Public Health is related to the search for optimal strategies to reach diverse populations, this review is interested in researching how low- and middle-income countries have designed and implemented communication interventions to promote vaccination, how the interventions have been evaluated and what results they had. It is highlighted that this review seeks, in particular, to learn about the messages that have been used to encourage vaccination.

The search of articles in English, Spanish, and Portuguese, will be conducted on the following databases: PubMed, Scopus, Web of Science, Redalyc and PyscInfo. The processes of search, selection, extraction and data analysis will be carried out by at least two researchers using Rayyan and Excel. The quality review will be performed using the QATSDD tool, that is valid to qualitative and quantitative studies.

In this protocol you will find the methodology in detail, such as the search strategies, databases used and more. The results of this study will be presented in another article.